About sildenafil citrate



Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and also to a lesser extent during the urine (close to thirteen% of the administered oral dose). If taken by using a superior-Body fat meal, absorption is diminished; the time taken to achieve the most plasma focus raises by all-around one hour, and the maximum concentration by itself is lessened by practically one particular-third.[37] Route of administration

Sildenafil should not be taken by folks who acquire nitrates for example nitroglycerin (glycerin trinitrate), as this will cause a extreme and potentially lethal drop in hypertension.[three]

VIAGRA may be taken with or with no foods. If you take VIAGRA after a high-fat food (like a cheeseburger and french fries), it may consider somewhat for a longer period to start out Functioning.

It can be crucial to help keep all medication away from sight and reach of youngsters as many containers (such as weekly tablet minders and people for eye drops, creams, patches, and inhalers) aren't youngster-resistant and youthful young children can open them quickly.

The first indication of sildenafil is treatment of erectile dysfunction (lack of ability to sustain a satisfactory erection to finish intercourse).

The health and fitness data contained herein is presented for educational applications only and isn't intended to replace discussions which has a Health care supplier. All conclusions concerning affected individual care must be manufactured having a healthcare service provider, looking at the exceptional qualities with the individual.

Efficacy, tolerability, cure fulfillment, as well as other close details have been measured at baseline and/or the top of your double-blind and open-label phases and as opposed involving placebo and sildenafil initiated at doses of fifty and a hundred mg.

Manufacture and sale of sildenafil citrate prescription drugs known as "generic Viagra" is prevalent in India, the place Pfizer's patent declare would not use.

Sildenafil (compound UK-ninety two,480) was synthesized by a bunch of pharmaceutical chemists Performing at Pfizer's Sandwich, Kent, investigate facility in England. It absolutely was originally researched for use in hypertension (large blood pressure) and angina pectoris (a symptom of ischaemic cardiovascular disease). The main scientific trials were being conducted in Morriston Hospital in Swansea.[forty one] Section I scientific trials underneath the route of Ian Osterloh proposed the drug experienced tiny effect on angina, but it could induce marked penile erections.

[29] Some tries are actually made to ban these medicine, but development is gradual so far, as, even in Individuals jurisdictions which have legislation concentrating on designer medication, the regulations are drafted to ban analogs of unlawful medications of abuse, as opposed to analogs of prescription medicines. Having said that, not less than just one courtroom case has resulted in a product getting taken off the market.[thirty]

This medicine is not expected to hurt an unborn infant. Tell your medical professional When you are Expecting or prepare to be pregnant.

Should you’ve tried VIAGRA and if you're still not getting final results, request your medical professional to see if adjusting your dose may support. Don't forget, VIAGRA should not be taken multiple time a day.

Tentative proof implies that sildenafil might enable men who knowledge antidepressant-induced erectile dysfunction.[7] click here Pulmonary hypertension

Some Uncomfortable side effects can be critical. In the event you working experience any of the next symptoms, phone your doctor instantly:

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